1293 FORAMEN OVALE ATRIAL SEPTAL RATIO: EVIDENCE FOR DIFFERENT PATHOGENIC MECHANISMS IN CONGENITAL HEART DEFECTS
نویسندگان
چکیده
منابع مشابه
Closure Devices for Patent Foramen Ovale and Atrial Septal Defects
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متن کاملCONGENITAL HEART DISEASE Inheritance of persistent foramen ovale and atrial septal defects and the relation to familial migraine with aura
Objective: To determine whether smaller atrial shunts (large persistent foramen ovale (PFO) and small atrial septal defect (ASD)) are inherited and whether this has a role in the inheritance of migraine with aura. Methods: Contrast echocardiography was used to detect atrial shunts in 71 relatives of 20 probands with a significantly sized atrial shunt (large PFO or ASD). Four families with three...
متن کاملA gain-of-function TBX20 mutation causes congenital atrial septal defects, patent foramen ovale and cardiac valve defects
BACKGROUND Ostium secundum atrial septal defects (ASDII) account for approximately 10% of all congenital heart defects (CHD), and mutations in cardiac transcription factors, including TBX20, were identified as an underlying cause for ASDII. However, very little is known about disease penetrance in families and functional consequences of inherited TBX20 mutations. METHODS The coding region of ...
متن کاملRecent advances in closure of atrial septal defects and patent foramen ovale
Transcatheter closure of secundum atrial septal defect (ASD) and patent foramen ovale (PFO) is now widely accepted as an alternative to surgical closure. With currently available devices and techniques, approximately 80-90% of secundum ASDs and all PFOs can be closed percutaneously. While many devices are available, the use of any particular device is dictated largely by individual defect anato...
متن کاملPatent Foramen Ovale and Atrial Septal Defect: Diagnosis and Therapy
Patent foramen ovale (PFO) and atrial septal defect (ASD) are frequent congenital heart defects in adults. While the indication for surgical or interventional closure of an ASD is sufficiently evaluated, the necessity of closing a PFO remains a topic of academic discussions. In this article we present epidemiological data, show the actual anatomic classification, highlight relevant aspects of p...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1985
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198504000-01317